ATLAS Biolabs - Laboratory services

ATLAS Biolabs offers molecular genetic services. These services include next-generation sequencing (NGS) and the analysis of microarrays as well as high-quality bioinformatic data analyses upon request. In addition to human samples, we also process biomaterial of common model organisms, such as mouse, rat, zebrafish, Drosophila etc. Furthermore, we analyse DNA and RNA of farm animals, plants (agrigenomics) as well as domestic animals and microorganisms.

ATLAS Biolabs' molecular genetics laboratory carries out its services according to the DIN EN ISO 9001:2015 standard, in order to demonstrate our competence and guarantee the quality of our services.

Our quality management

ATLAS Biolabs offers innovative Next Generation Sequencing (NGS) services. We support you with the highest precision and efficiency - from analysing genetic variants to comprehensive multi-omics strategies for research and clinical applications.

More about DNA and epigenome sequencing

ATLAS Biolabs is expanding its portfolio to include state-of-the-art proteomics services. With innovative technologies and in-depth expertise, we support you in the comprehensive analysis of protein profiles - as a single study or embedded in complex multi-omics projects.

More about proteomics

The causes of genetic diseases can be identified by digital karyotyping, such as copy number variations (CNV), amplifications, deletions, loss of heterozygosity (LOH) or copy-number-neutral LOH (uniparental disomy). Karyotyping based on oligonucleotides using microarrays is characterised by a very high resolution with distances of a few kilobase (kb) only. Depending on the type of microarray, the probes are located at an average distance of 1 kb. We use technologies from Thermo Fisher Scientific/Affymetrix, such as CytoScan and Agilent Technologies (CGH, SurePrint).

More about karyotyping

We analyse the DNA of your FFPE material using the OncoScan FFPE assay kit (Thermo Fisher Scientific/Affymetrix). This kit ensures a very high resolution (50-100 kb) of the DNA of more than 900 cancer genes. It also allows the analysis of somatic mutations. The dynamic range is 10 copies or more. The method furthermore allows the genome-wide analysis of copy number variations (CNV) and loss of heterozygosity (LOH).

More about oncogene analyses

Our focus is also on genetic variations that are influenced by drug uptake or absorption, distribution, metabolism and excretion (ADME). For these cases, ATLAS Biolabs uses special technologies for the investigation of pharmacogenetically relevant genes and markers (PGx), e.g. the Thermo Fisher Scientific/Axiom PharmacoScan.

More about pharmacogenetics

Microbiome analyses should be considered for analysing microbial communities. These communities, found, for example, in the intestines of humans and animals, but also in plants, have a manifold influence on metabolism and thus on further processes.

More about microbiome analyses

Transcriptome analyses provide a better understanding of how the genome is transformed into functional proteins. Their clinical benefit is that they permit expression profiles to be classified, which also constitutes a meaningful contribution to individualised medicine. We offer two powerful technologies for transcriptome analysis: hybridisation-based microarray technology and RNA sequencing.

More about transcriptome analyses